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Anderson MM, Hazen SL, Hsu FF, Heinecke JW (1997) Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. Kinetics and Mechanism of Protein Tyrosine Phosphatase 1B Inactivation by Acrolein. The biological buffer, bicarbonate/CO2, potentiates H2O2-mediated inactivation of protein tyrosine phosphatases. Oxidative inactivation of PTP1B by natural peroxides. Dry …
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